Windows 11 why some apps can't start after clearing up space on windows

[repulsion]

I use a Windows 11 computer. When I clean up the disk space on my computer, whether I use bleachbit or clean up unnecessary files in the file manager, every time I finish cleaning, some applications cannot be opened. When I click on the icon in the menu bar, a rectangular box pops up in the middle of the screen, indicating that the application cannot be found. The applications that encounter this situation are the edge browser and anaconda navigator and so on. After my research, I found that there is a very important problem after cleaning. The size of the exe files pointed to by the shortcuts

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